![Crystals of [2-(1-methyl-1H-pyrazol-4-yl)-6(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and pharmaceutically acceptable salt thereof](/docs/US/2020-11-03/US10822336B2/abs.jpg.600x600.jpg)
- Patent Title: Crystals of [2-(1-methyl-1H-pyrazol-4-yl)-6(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and pharmaceutically acceptable salt thereof
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Application No.: US16337664Application Date: 2017-09-28
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Publication No.: US10822336B2Publication Date: 2020-11-03
- Inventor: Yasushi Ueda , Sagar Ramdas Amale , Manjunath Govind Bhovi
- Applicant: Daiichi Sankyo Company, Limited
- Applicant Address: JP Tokyo
- Assignee: Daiichi Sankyo Company, Limited
- Current Assignee: Daiichi Sankyo Company, Limited
- Current Assignee Address: JP Tokyo
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@63ec5beb
- International Application: PCT/JP2017/035205 WO 20170928
- International Announcement: WO2018/062382 WO 20180405
- Main IPC: C07D473/34
- IPC: C07D473/34 ; A61P11/00 ; A61P11/06 ; A61P19/02 ; A61P35/00 ; A61P37/06 ; A61P37/08 ; A61P37/02 ; A61P17/06 ; A61K31/5377 ; A61P29/00
![Crystals of [2-(1-methyl-1H-pyrazol-4-yl)-6(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and pharmaceutically acceptable salt thereof](/abs-image/US/2020/11/03/US10822336B2/abs.jpg.150x150.jpg)
Abstract:
Provided are novel crystals of [2-(1-methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and a pharmaceutically acceptable salt thereof having advantageous characteristics. [2-(1-Methyl-1H-pyrazol-4-yl)-6-(morpholin-4-yl)-9H-purin-8-yl][4-(morpholin-4-yl)piperidin-1-yl]methanone and a pharmaceutically acceptable salt thereof provided by the present invention are excellent in stability and have satisfactory physical properties as a drug substance of a pharmaceutical product.
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