An image sensing device including a noise blocking structure is disclosed. The image sensing device includes a semiconductor substrate structured to support a plurality of image pixels producing signals response to received incident light, a logic circuit configured to process the signals read out from the image pixels, and a noise blocking structure coupled to the logic circuit to reduce a noise generated by the logic circuit. The noise blocking structure formed to extend in a straight line without any bending portion in a first direction, and to pass through the semiconductor substrate in a second direction that is perpendicular to the first direction.