Invention Grant
- Patent Title: Combination of anti-FGFR4-antibody and bile acid sequestrant
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Application No.: US15575255Application Date: 2016-05-18
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Publication No.: US10765738B2Publication Date: 2020-09-08
- Inventor: Reimar Abraham , Mauricio Redondo-Müller
- Applicant: Daiichi Sankyo Europe GmbH , DAIICHI SANKYO COMPANY LIMITED
- Applicant Address: DE Munich JP Tokyo
- Assignee: Daiichi Sankyo Europe GmbH,Daiichi Sankyo Company Limited
- Current Assignee: Daiichi Sankyo Europe GmbH,Daiichi Sankyo Company Limited
- Current Assignee Address: DE Munich JP Tokyo
- Agency: Withers & Keys, LLC
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@455b5ecc
- International Application: PCT/EP2016/061131 WO 20160518
- International Announcement: WO2016/184909 WO 20161124
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K31/07 ; A61K31/122 ; A61K31/355 ; A61K31/785 ; C07K16/28 ; A61K39/00 ; A61K31/59 ; A61K31/787 ; A61K45/06 ; A61K38/17 ; A61P21/00 ; A61P9/00 ; A61P3/04 ; A61P3/10 ; A61P13/12 ; A61P35/00 ; A61K31/395
Abstract:
The present invention relates to the amelioration of toxic effects that are caused by therapies aimed at FGFR4-inhibition. In particular, the invention relates to the combination of FGFR4 inhibitors and agents capable of reducing bile acid levels and to the use thereof in the treatment of diseases.
Public/Granted literature
- US20180133312A1 COMBINATION OF ANTI-FGFR4-ANTIBODY AND BILE ACID SEQUESTRANT Public/Granted day:2018-05-17
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