- Patent Title: In vitro production of medial ganglionic eminence precursor cells
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Application No.: US16126594Application Date: 2018-09-10
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Publication No.: US10760048B2Publication Date: 2020-09-01
- Inventor: Cory R. Nicholas , John L. Rubenstein , Arnold R. Kriegstein , Arturo Alvarez-Buylla
- Applicant: The Regents of the University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Bozicevic, Field & Francis LLP
- Agent Shweta Chandra
- Main IPC: C12N5/079
- IPC: C12N5/079 ; C12N5/0793 ; C12N15/63
Abstract:
Methods and systems for generating MGE precursor cells in vitro as well as compositions of enriched MGE precursor cells are provided. The methods and systems provide efficient production of MGE precursors. The methods and systems disclosed herein provide functional MGE precursors which differentiate into functional GABAergic interneurons.
Public/Granted literature
- US20190062700A1 In Vitro Production of Medial Ganglionic Eminence Precursor Cells Public/Granted day:2019-02-28
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