Invention Grant
- Patent Title: Water soluble nitric oxide-releasing polyglucosamines and uses thereof
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Application No.: US15836121Application Date: 2017-12-08
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Publication No.: US10759877B2Publication Date: 2020-09-01
- Inventor: Mark H. Schoenfisch , Yuan Lu
- Applicant: The University of North Carolina at Chapel Hill
- Applicant Address: US NC Chapel Hill
- Assignee: The University of North Carolina at Chapel Hill
- Current Assignee: The University of North Carolina at Chapel Hill
- Current Assignee Address: US NC Chapel Hill
- Agency: Alston & Bird LLP
- Main IPC: C08B37/00
- IPC: C08B37/00 ; C08B37/08 ; A61K47/60 ; C08L5/08
Abstract:
The presently disclosed subject matter provides nitric oxide-releasing polysaccharides and oligosaccharides, in particular, polyglucosamines, and their use in biomedical and pharmaceutical applications. More particularly, in some embodiments, the presently disclosed subject matter provides nitric oxide-releasing polysaccharides and oligosaccharides that release nitric oxide in a controlled and targeted manner, thereby prolonging the therapeutic effects of nitric oxide and improving the specificity of nitric oxide delivery to targeted cells and/or tissues.
Public/Granted literature
- US20180162956A1 WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF Public/Granted day:2018-06-14
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