Invention Grant
- Patent Title: Neuroactive steroids, compositions, and uses thereof
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Application No.: US16114791Application Date: 2018-08-28
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Publication No.: US10759828B2Publication Date: 2020-09-01
- Inventor: Ravindra B. Upasani , Boyd L. Harrison , Benny C. Askew , Jean-Cosme Dodart , Francesco G. Salituro , Albert Jean Robichaud
- Applicant: Sage Therapeutics, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Sage Therapeutics, Inc.
- Current Assignee: Sage Therapeutics, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Main IPC: C07J1/00
- IPC: C07J1/00 ; C07J7/00 ; C07J75/00 ; C07J41/00 ; C07J9/00 ; C07J3/00 ; C07J31/00 ; C07J43/00
Abstract:
Compounds are provided according to Formula (I): and pharmaceutically acceptable salts thereof, wherein Z is a group of the formula (i), (ii), (iii), (iv), or (v): and wherein L1, L2, L3, X1, X2, Y, RZ4, RZ5, RZ6, n, R1, R2, R3a, R3b, R4a, R4b, R6a, R6b, R7a, R7b, R11a, R11b, R14, R17, R19, R20, R23a, R23b, and R24 are as defined herein, and pharmaceutical compositions thereof. Compounds of the present invention are contemplated useful for the prevention and treatment of a variety of CNS-related conditions in mammals.
Public/Granted literature
- US20180362573A1 NEUROACTIVE STEROIDS, COMPOSITIONS, AND USES THEREOF Public/Granted day:2018-12-20
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