Invention Grant
- Patent Title: Separation of cells based on size and affinity using paper microfluidic device
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Application No.: US16033261Application Date: 2018-07-12
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Publication No.: US10758846B2Publication Date: 2020-09-01
- Inventor: Charles R. Mace , Syrena C. Fernandes , Samuel B. Berry
- Applicant: Trustees of Tufts College
- Applicant Address: US MA Medford
- Assignee: Trustees of Tufts College
- Current Assignee: Trustees of Tufts College
- Current Assignee Address: US MA Medford
- Agency: Nixon Peabody LLP
- Main IPC: B01D29/01
- IPC: B01D29/01 ; B01D39/18 ; G01N33/49 ; B01D29/58 ; G01N33/574 ; G01N31/22

Abstract:
A microfluidic device includes a first layer of a porous material with pores having a first average pore size and a liquid-receiving area through which a liquid sample is received into the microfluidic device. A second layer of another porous material, with pores of a second average pore size, is stacked below the first layer and has a channel with a starting end positioned at least in part in an overlapping manner with the liquid-receiving area. The channel has a terminating end extending laterally at a predetermined wicking distance from the starting end. The first average pore size and the second average pore size cause a wicking effect in which at least some of the liquid sample flows along the channel at least a portion of the wicking distance between the starting end and the terminating end.
Public/Granted literature
- US20180318732A1 Separation Of Cells Based On Size And Affinity Using Paper Microfluidic Device Public/Granted day:2018-11-08
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