Invention Grant
- Patent Title: Vaccine in the form of a recombinant sero type 9 avian adenovirus vector
-
Application No.: US15502443Application Date: 2015-08-06
-
Publication No.: US10758608B2Publication Date: 2020-09-01
- Inventor: Bernardo Lozano-Dubernard , Ernesto Soto-Priante , David Sarfati-Mizrahi
- Applicant: GRUPO INDUSTRIAL PECUARIO, S.A. DE C.V.
- Applicant Address: MX Mexico City
- Assignee: GRUPO INDUSTRIAL PECUARIO, S.A. DE C.V.
- Current Assignee: GRUPO INDUSTRIAL PECUARIO, S.A. DE C.V.
- Current Assignee Address: MX Mexico City
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@21af015d
- International Application: PCT/IB2015/055994 WO 20150806
- International Announcement: WO2016/020885 WO 20160211
- Main IPC: A61K39/145
- IPC: A61K39/145 ; A61K39/245 ; C07K14/005 ; C12N15/86 ; C12N7/00 ; A61K39/12 ; A61K39/00

Abstract:
A recombinant vaccine comprising a serotype 9 fowl adenovirus vector (FAdV-9) having at least one exogenous nucleotide sequence inserted encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region, and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the at least one exogenous nucleotide sequence encoding at least one antigen of a disease of interest and replacing the adenovirus genome non-essential region is located between the 491 and 2782 nucleotides. The vector of this vaccine is stable for industrial scale production. When administering this vaccine in combination with a vaccine against Marek's disease, both vaccines produce an adequate immune response which is not affected by interference between each other. In the same way, effectiveness of the recombinant vaccine is not affected by maternal antibodies, and is capable of inducing both an early and lasting protective response, even with only one application.
Public/Granted literature
- US20170232096A1 VACCINE IN THE FORM OF A RECOMBINANT SERO TYPE 9 AVIAN ADENOVIRUS VECTOR Public/Granted day:2017-08-17
Information query