Invention Grant
- Patent Title: Cytotoxic agents that preferentially target leukemia inhibitory factor (LIF) for the treatment of malignancies and as new contraceptive agents
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Application No.: US16038735Application Date: 2018-07-18
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Publication No.: US10738075B2Publication Date: 2020-08-11
- Inventor: Hareesh Nair , Bindu Santhamma , Klaus Nickisch
- Applicant: Evestra, Inc.
- Applicant Address: US TX Schertz
- Assignee: Evestra, Inc.
- Current Assignee: Evestra, Inc.
- Current Assignee Address: US TX Schertz
- Agency: Kowert, Hood, Munyon, Rankin & Goetzel, P.C.
- Agent Mark R. DeLuca
- Main IPC: C07J1/00
- IPC: C07J1/00 ; C07J11/00 ; C07J31/00 ; C07J41/00 ; C07J43/00 ; C07J21/00 ; C07J51/00 ; C07J71/00
Abstract:
Described herein are new anti-cancer compounds and methods of using such compounds, acting through a new mechanism of action by simultaneous inhibition of leukemia inhibitory factor (LIF) and MDM2.
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