Invention Grant
- Patent Title: GLS1 inhibitors for treating disease
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Application No.: US16152901Application Date: 2018-10-05
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Publication No.: US10738043B2Publication Date: 2020-08-11
- Inventor: Richard Thomas Lewis , Philip Jones , Alessia Petrocchi , Naphtali Reyna , Matthew Hamilton , Michael J. Soth , Timothy Heffernan , Michelle Han , Jason P. Burke
- Applicant: Board of Regents, The University of Texas System
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Dennis A. Bennett; Cynthia Hathaway; John Desper
- Main IPC: C07D417/14
- IPC: C07D417/14 ; A61K31/501 ; A61K45/06 ; C07D403/14 ; C07D401/14 ; A61K31/454 ; A61K31/4545 ; A61K31/4439

Abstract:
Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.
Public/Granted literature
- US20190031651A1 GLS1 INHIBITORS FOR TREATING DISEASE Public/Granted day:2019-01-31
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