Invention Grant
![Crystalline form of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide](/docs/US/2020-08-11/US10738037B2/abs.jpg.600x600.jpg)
- Patent Title: Crystalline form of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide
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Application No.: US16301826Application Date: 2017-05-18
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Publication No.: US10738037B2Publication Date: 2020-08-11
- Inventor: Ilaria Candiani , Giovanni Ottaiano , Attilio Tomasi
- Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
- Applicant Address: IT Nerviano (MI)
- Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
- Current Assignee: NERVIANO MEDICAL SCIENCES S.R.L.
- Current Assignee Address: IT Nerviano (MI)
- Agency: Scully, Scott, Murphy & Presser, P.C.
- International Application: PCT/EP2017/061919 WO 20170518
- International Announcement: WO2017/202674 WO 20171130
- Main IPC: C07D405/12
- IPC: C07D405/12 ; C07D405/14 ; A61P35/00
![Crystalline form of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide](/abs-image/US/2020/08/11/US10738037B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a new crystalline form of N-[5-(3,5-difluoro-benzyl)-1H-indazol-3-yl]-4-(4-methyl-piperazin-1-yl)-2-(tetrahydro-pyran-4-ylamino)-benzamide, process for its preparation, its utility in treating diseases caused by deregulated protein kinase activity and pharmaceutical compositions containing it.
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