A cable-operated mechanism for actuating a slide-out room includes a column, an endless chain loop disposed with the column, first and second drive blocks engaged with the chain loop, and first through fourth cables attached at first ends thereof to the drive blocks. The cables are attached at second ends thereof to inboard and outboard ends of a slide out room. Operation of the chain loop in a first direction tensions the cables attached to the inboard end of the room and slackens the cables attached to the outboard end. Operation of the chain loop in a second direction has the opposite effect.