Apparatuses and methods for transmitting and receiving signals in a mobile communication system are provided. A method for transmitting a signal by an evolved Node B (eNB) in a mobile communication system includes transmitting a same control channel signal to each of a plurality of Radio Units (RUs), and transmitting a different data channel signal to each of the plurality of RUs. A data channel signal transmitted to each of the plurality of RUs may be determined taking into account at least one of a location of a User Equipment (UE) that will receive the data channel signal, and load balancing.