A distributed antenna system supporting MIMO service is disclosed. Some embodiments provide a distributed antenna system supporting MIMO communication, including first node, second node and one transmission line. The first node receives MIMO downlink signals of a plurality of MIMO services each including N (a natural number of 2 or more) MIMO downlink signals, and performs, for each MIMO service, frequency-conversion of N−1 MIMO downlink signals among the N MIMO downlink signals, to different frequency band from original frequency band, to generate N MIMO downlink signals without mutually overlapping frequency bands. The second node performs, for each MIMO service, frequency-conversion of the MIMO downlink signals having been frequency-converted by first node, in a complementary manner, to reconstruct the MIMO downlink signals of original frequency band. The single transmission line is used between the first node and second node for transmitting N downlink signals without mutually overlapping frequency bands.