The present disclosure provides an organic light-emitting diode (OLED) substrate and a method for manufacturing same. The method includes providing a substrate that includes a non-pixel area, a first pixel area, a second pixel area, and a third pixel area; forming a first sacrificial layer in the first pixel area and the second pixel area, forming a third light-emitting material layer on the substrate, and removing the first sacrificial layer, so as to form a third pixel area organic layer; and using the same steps to form a second pixel area organic layer and a first pixel area organic layer.