An electronic device to autofocus on an object-of-interest within a field-of-view of the electronic device, includes an image sensor and a circuitry. The image sensor captures a sequence of image frames that includes a current frame and detect at least one prominent region in the current frame. The detected at least one prominent region has an optical flow similar to a direction of motion of the electronic device. The circuitry selects a region-of-interest from the detected at least one prominent region and estimates an autofocus point in the detected at least one prominent region. The circuitry controls focus of the image sensor at the estimated autofocus point in the current frame. The focus of the image sensor is controlled such that the estimated autofocus point exhibits a minimum deviation from an initialized position for the estimated autofocus point within the detected at least one prominent region.