Invention Grant
- Patent Title: Immuno-based botulinum toxin serotype A activity assays
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Application No.: US15400618Application Date: 2017-01-06
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Publication No.: US10703806B2Publication Date: 2020-07-07
- Inventor: Ester Fernandez-Salas , Joanne Wang , Patton Garay , Lina S. Wong , D. Dianne Hodges , Kei Rogers Aoki
- Applicant: Allergan, Inc.
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Brigitte C. Phan
- Main IPC: G01N33/566
- IPC: G01N33/566 ; C07K16/12 ; G01N33/68 ; C12Q1/37 ; G01N33/50
Abstract:
The present specification discloses SNAP-25 compositions, methods of making α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing α-BoNT/A antibodies.
Public/Granted literature
- US20170283487A1 IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS Public/Granted day:2017-10-05
Information query
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