Invention Grant
- Patent Title: Compositions comprising an inhibitor of lysine specific demethylase-1
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Application No.: US16436541Application Date: 2019-06-10
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Publication No.: US10703739B2Publication Date: 2020-07-07
- Inventor: Young K. Chen , Toufike Kanouni , Stephen W. Kaldor , Jeffrey Alan Stafford , James Marvin Veal , Paula Alessandra Tavares-Greco , Matthew Michael Kreilein
- Applicant: Celgene Quanticel Research, Inc.
- Applicant Address: US CA San Diego
- Assignee: Calgene Quanticel Research, Inc.
- Current Assignee: Calgene Quanticel Research, Inc.
- Current Assignee Address: US CA San Diego
- Agency: Foley & Lardner LLP
- Main IPC: C07D239/36
- IPC: C07D239/36 ; C07D401/04 ; A61K31/4545 ; A61K31/506 ; A61P35/00

Abstract:
Described herein are amorphous and crystalline forms of pharmaceutically acceptable salts of the lysine specific demethylase-1 inhibitor 4-[2-(4-aminopiperidin-1-yl)-5-(3-fluoro-4-methoxy-phenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-4-yl]-2-fluorobenzonitrile. Also described are pharmaceutical compositions suitable for administration to a mammal that include the lysine specific demethylase-1 inhibitor, and methods of using the lysine specific demethylase-1 inhibitor for treating diseases or conditions that are associated with lysine specific demethylase-1 activity.
Public/Granted literature
- US20190367473A1 COMPOSITIONS COMPRISING AN INHIBITOR OF LYSINE SPECIFIC DEMETHYLASE-1 Public/Granted day:2019-12-05
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