![Process for the preparation of Trisodium (4- {[1S,3R)-1-([1,1′-biphenyl]-4-ylmethyl)-4-ethoxy-3-methyl-4-oxobutyl]amino}-4-oxobutanoate)-(N-petanoyl-N-{[2′-(1H-tetrazol-1-1D-5-yl)[1,1′-biphenyl]-4-yl]methyl}- L-valinate) and its polymorphs thereof](/docs/US/2020-07-07/US10703731B2/abs.jpg.600x600.jpg)
- Patent Title: Process for the preparation of Trisodium (4- {[1S,3R)-1-([1,1′-biphenyl]-4-ylmethyl)-4-ethoxy-3-methyl-4-oxobutyl]amino}-4-oxobutanoate)-(N-petanoyl-N-{[2′-(1H-tetrazol-1-1D-5-yl)[1,1′-biphenyl]-4-yl]methyl}- L-valinate) and its polymorphs thereof
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Application No.: US16083784Application Date: 2017-03-06
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Publication No.: US10703731B2Publication Date: 2020-07-07
- Inventor: Thirumalai Rajan Srinivasan , Eswaraiah Sajja , Rajeshwar Reddy Sagyam , Rajesham Boge , Chkradhar Nandigama , Srinivasa Rao Ambati
- Applicant: MSN LABORATORIES PRIVATE LIMITED
- Applicant Address: IN Hyderabad, Telangana
- Assignee: MSN LABORATORIES PRIVATE LIMITED
- Current Assignee: MSN LABORATORIES PRIVATE LIMITED
- Current Assignee Address: IN Hyderabad, Telangana
- Agency: IP Pundit LLC
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@3185da95 com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@2eed31c3
- International Application: PCT/IN2017/000056 WO 20170306
- International Announcement: WO2017/154017 WO 20170914
- Main IPC: C07D257/04
- IPC: C07D257/04 ; C07C233/47 ; C07C231/12 ; B01D9/00 ; A61K47/12 ; A61K47/38 ; A61K47/32 ; A61K47/10 ; A61K9/10
![Process for the preparation of Trisodium (4- {[1S,3R)-1-([1,1′-biphenyl]-4-ylmethyl)-4-ethoxy-3-methyl-4-oxobutyl]amino}-4-oxobutanoate)-(N-petanoyl-N-{[2′-(1H-tetrazol-1-1D-5-yl)[1,1′-biphenyl]-4-yl]methyl}- L-valinate) and its polymorphs thereof](/abs-image/US/2020/07/07/US10703731B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to a process for the preparation of Trisodium (4-{[(1S.3R)-1-([1,1′-biphenyl]-4-yl-methyl)-4-ethoxy-3-methyl-4-oxobutyl]amino}-4-oxo butanoate)-(N-pentanoyl-N-{[2′-(1H-tetrazol-1-id-5-yl)[1,1′-biphenyl]-4-yl]methyl}-L-valinate) represented by the following structural formula-1:
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