A composite manufacturing method with extruding and turning process for extruding and turning a workpiece includes a clamping step, an isolating step, an extruding step and a turning step. The composite manufacturing method is used for manufacturing a surgical instrument. The clamping step is for positioning a clamping portion of the workpiece by a lathe chuck of the lathe apparatus. The isolating step is for blocking a lathe extruding force via an isolating portion of an extruding apparatus. The extruding step is for extruding a processing end portion of the workpiece by the extruding apparatus and generating the lathe extruding force transmitted toward a clamping portion of the workpiece. The turning step is for turning the processing end portion of the extruded workpiece by a lathe apparatus. The extruding apparatus is disposed on the lathe apparatus.