An apparatus (20) includes a probe (36) and a processor (144). The probe is positioned adjacent to an eye (28) of a patient (32) and is configured to irradiate a trabecular meshwork (56) of the eye with one or more optical beams (52). The processor is configured to select one or more target regions (80) of the trabecular meshwork, and to control the probe to irradiate the selected target regions with the optical beams.