Invention Grant
- Patent Title: Bivalent siRNA chimeras and methods of use thereof
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Application No.: US15726851Application Date: 2017-10-06
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Publication No.: US10689654B2Publication Date: 2020-06-23
- Inventor: Hong Yan Liu
- Applicant: Augusta University Research Institute, Inc.
- Applicant Address: US GA Augusta
- Assignee: Augusta University Research Institute, Inc.
- Current Assignee: Augusta University Research Institute, Inc.
- Current Assignee Address: US GA Augusta
- Agency: Smith, Gambrell & Russell, LLP
- Main IPC: C12N15/115
- IPC: C12N15/115 ; C12N15/113 ; A61K47/54 ; A61K31/713 ; A61K45/06
Abstract:
A bivalent siRNA chimera platform capable of efficiently delivering and silencing two or more genes in vivo or in vitro is provided. Methods of using the bivalent siRNA chimeras for selectively targeting cells to down-regulate the expression of multiple genes are also provided.
Public/Granted literature
- US20180105815A1 Bivalent siRNA Chimeras and Methods of Use Thereof Public/Granted day:2018-04-19
Information query
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