Invention Grant
- Patent Title: Theranostic bubble preparation (TB), and method for using same
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Application No.: US15579140Application Date: 2016-06-10
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Publication No.: US10688199B2Publication Date: 2020-06-23
- Inventor: Kazuo Maruyama , Ryo Suzuki , Johan Mikael Unga , Daiki Omata , Yusuke Oda
- Applicant: TEIKYO UNIVERSITY
- Applicant Address: JP Tokyo
- Assignee: TEIKYO UNIVERSITY
- Current Assignee: TEIKYO UNIVERSITY
- Current Assignee Address: JP Tokyo
- Agency: Alston & Bird LLP
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@39736a0a
- International Application: PCT/JP2016/002810 WO 20160610
- International Announcement: WO2016/199430 WO 20161215
- Main IPC: A61K49/22
- IPC: A61K49/22 ; A61K31/02 ; A61K47/69 ; A61P35/00 ; A61K9/00 ; A61K9/19 ; A61K47/24 ; A61K47/36 ; A61K47/42
Abstract:
Provided is a theranostic bubble preparation which makes it possible to diagnose and treat a tissue of interest by the irradiation with ultrasound such as diagnostic ultrasound and low-intensity therapeutic ultrasound. The theranostic bubble preparation comprises: a coating film comprising a lipid; and a gas enclosed in an inner cavity formed in the coating film. The coating film comprises an anionic lipid made from distearoylphosphatidylcholine (DSPC), distearoylphosphatidylglycerol (DSPG) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000). The gas and the mixed gas comprises perfluoropropane or perfluorobutane.
Public/Granted literature
- US20180161462A1 THERANOSTIC BUBBLE PREPARATION (TB), AND METHOD FOR USING SAME Public/Granted day:2018-06-14
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