An X-ray diagnostic apparatus according to one embodiment comprises an X-ray tube, an X-ray detector, a holding mechanism, position specifying circuitry and control circuitry. The X-ray detector detects the X-ray which has been generated by the X-ray tube and has passed through an object placed on a top of a bed movable in an examination room. The holding mechanism holds the X-ray tube and the X-ray detector, and movable in the examination room. The position specifying circuitry specifies a position of the holding mechanism in the examination room and a position of the bed in the examination room. The control circuitry controls the holding mechanism in order to change a position and angle of the holding mechanism based on the position of the holding mechanism and the position of the bed.