Invention Grant
- Patent Title: Gastric retention active delivery systems
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Application No.: US15774395Application Date: 2016-10-27
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Publication No.: US10682307B2Publication Date: 2020-06-16
- Inventor: Andrea Engel , Thomas Gottstein , Melanie Liefke
- Applicant: Evonik Operations GmbH
- Applicant Address: DE Essen
- Assignee: Evonik Operations GmbH
- Current Assignee: Evonik Operations GmbH
- Current Assignee Address: DE Essen
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: com.zzzhc.datahub.patent.etl.us.BibliographicData$PriorityClaim@5009bcc2
- International Application: PCT/EP2016/075872 WO 20161027
- International Announcement: WO2017/080833 WO 20170518
- Main IPC: A61K9/46
- IPC: A61K9/46 ; A61K9/00 ; A61K9/48 ; A61K31/05 ; A61K36/185

Abstract:
The present invention relates to a gastric retention active delivery system in the form of a coated capsule, which, in contrast to prior art delivery systems exhibiting relatively poor floating-properties, and thus requiring size expansion capability in order to securely delay passage through the pylorus, reliably stay afloat for several hours. This is achieved by combining pore forming components and flexible polymer components in the coating in suitable proportions. The present invention, further, relates to the use of gastric retention active delivery systems of the invention for the delivery of one or more water soluble active components A to a mammal.
Public/Granted literature
- US20190282493A1 GASTRIC RETENTION ACTIVE DELIVERY SYSTEMS Public/Granted day:2019-09-19
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