An object of the present invention is to provide a gas barrier film which can prevent the damage of an inorganic layer even in a case where the gas barrier film is used in a product which undergoes a step of applying pressure, heat, and the like, a solar cell using the gas barrier film, and a manufacturing method of the gas barrier film. The object is achieved by a gas barrier film having a support and an inorganic layer and a protective organic layer on one surface of the support, in which the protective organic layer has a polymerized substance of a graft copolymer having an acryl polymer as a main chain and having, as a side chain, at least either an acryloyl group-terminated urethane polymer or an acryloyl group-terminated urethane oligomer, a polymerized substance of a (meth)acrylate monomer having three or more functional groups, a polymerized substance of the graft copolymer and the (meth)acrylate monomer having three or more functional groups, a (meth)acrylate polymer, and a silane coupling agent having a (meth)acryloyl group.