Invention Grant
- Patent Title: Cyclic peroxides as prodrugs for selective delivery of agents
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Application No.: US16364577Application Date: 2019-03-26
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Publication No.: US10662215B2Publication Date: 2020-05-26
- Inventor: Adam R. Renslo , Erica M. W. Lauterwasser , Shaun D. Fontaine , Benjamin B. Spangler , James A. Wells
- Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Applicant Address: US CA Oakland
- Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
- Current Assignee Address: US CA Oakland
- Agency: Mintz, Levin, Cohn, Ferris, Glovsky and Popeo, P.C.
- Agent Doris Lee
- Main IPC: C07D405/14
- IPC: C07D405/14 ; A61K31/4709 ; C07H19/16 ; C07F7/18 ; C07D407/12 ; C07D323/02 ; C07D405/12 ; C07D417/12 ; C07D417/14 ; C07D471/14 ; C07D493/04 ; C07D519/04 ; C07F9/655 ; C07H19/06 ; C07H19/167 ; A61K47/64 ; A61K47/68 ; C07F9/6558 ; A61K31/357 ; A61K31/4025 ; A61K31/404 ; A61K31/4192 ; A61K31/427 ; A61K31/435 ; A61K31/437 ; A61K31/444 ; A61K31/4745 ; A61K31/496 ; A61K31/4985 ; A61K31/513 ; A61K31/662 ; A61K31/7072 ; A61K31/7076 ; A61K31/7135 ; A61K51/04 ; C07D487/04 ; C07D491/107 ; C07D491/113 ; C07D491/153 ; C07D493/14 ; C07K7/06
Abstract:
Disclosed herein, inter alia, are prodrug compositions and methods of using the same for treatment and detection of disease. Specifically, disclosed herein is a compound of formula (I) having spiro-fused 1,2,4-trioxolane and piperidine rings, namely, 1,2,4-trioxa-8-azaspiro[4.5]decane. Also disclosed is a pharmaceutical composition containing the compound and a pharmaceutically acceptable carrier.
Public/Granted literature
- US20190284224A1 CYCLIC PEROXIDES AS PRODRUGS FOR SELECTIVE DELIVERY OF AGENTS Public/Granted day:2019-09-19
Information query
