Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
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Application No.: US16006105Application Date: 2018-06-12
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Publication No.: US10662192B2Publication Date: 2020-05-26
- Inventor: Sara Hadida-Ruah , Anna Hazlewood , Peter Grootenhuis , Fredrick Van Goor , Ashvani Singh , Jinglan Zhou , Jason McCartney
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07C205/11
- IPC: C07C205/11 ; C07C205/58 ; C07D471/10 ; C07C211/17 ; C07C209/00 ; C07C215/28 ; C07D209/08 ; C07D209/14 ; C07D209/18 ; C07D209/42 ; C07D209/94 ; C07D213/20 ; C07D213/73 ; C07D215/227 ; C07D215/38 ; C07D217/06 ; C07D223/16 ; C07D265/36 ; C07D279/16 ; C07D311/58 ; C07D401/14 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07C215/76 ; C07D215/56 ; C07D401/12 ; C07D215/233 ; A61K8/49 ; A61K31/47 ; A61K31/4709 ; A61K45/06 ; C07C215/78 ; C07C217/84 ; C07D209/12 ; C07D209/20 ; A61K31/136 ; A61K31/265 ; A61K31/352 ; A61K31/404 ; A61K31/4045 ; A61K31/4747 ; A61K31/55 ; C07C219/34 ; G01N33/566 ; G01N33/487 ; G01N33/50 ; G01N33/68 ; C07C217/80 ; C07C229/52 ; A61K31/04 ; A61K31/27 ; A61K31/277 ; A61K31/403 ; A61K31/44 ; A61K31/472 ; A61K31/538 ; A61K31/5415 ; C07C211/50 ; C07C211/52 ; C07C215/70 ; C07C217/76 ; C07C255/58 ; C07C271/20 ; C07C311/08 ; C07C311/39 ; C07D209/04 ; C07D209/96 ; C07D217/04
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20190144450A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Public/Granted day:2019-05-16
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