Invention Grant
- Patent Title: Fusion proteins comprising modified alpha virus surface glycoproteins and tumor associated antigen and methods thereof
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Application No.: US15558918Application Date: 2016-03-18
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Publication No.: US10660948B2Publication Date: 2020-05-26
- Inventor: Peter Leonardi , Elin Martina Pola , Jeffrey Babad
- Applicant: OMNICYTE
- Applicant Address: US NY New York
- Assignee: OMNICYTE
- Current Assignee: OMNICYTE
- Current Assignee Address: US NY New York
- Agency: Leason Ellis LLP
- International Application: PCT/US2016/023203 WO 20160318
- International Announcement: WO2016/149643 WO 20160922
- Main IPC: C12N15/00
- IPC: C12N15/00 ; A61K39/00 ; C07K14/005 ; A61K39/385 ; A61P35/00
Abstract:
The present disclosure relates to fusion proteins that comprise one or more modified alpha virus surface glycoproteins and one or more tumor specific antigens. Also disclosed are fusion proteins that comprise one or more modified alpha virus surface glycoproteins and one or more viral specific antigens. Also disclosed are fusion proteins that comprise one or more modified alpha virus surface glycoproteins. It also relates to methods to activate the immune system in cancer patients to infiltrate and kill tumor cells or cells infected with a latent virus. The present disclosure provides a platform technology that elicits a faster, broader and stronger immune response using the fusion proteins.
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Information query
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