A differential pair group equalization system includes a board providing a differential trace pair group with a plurality of differential trace pairs, each of a transmitter device and a receiver device are coupled to the board and the differential trace pairs in the differential trace pair group. At least one of the transmitter device and the receiver device operates to identify a first differential trace pair in the differential trace pair group, and adjust second differential trace pair equalization parameters for a second differential trace pair in the differential trace pair group. If it is determined that first differential trace pair signal transmission capabilities for the first differential trace pair have improved in response to the adjustment of the second differential trace pair equalization parameters for the second differential trace pair the second differential trace pair equalization parameters are set for the second differential trace pair.