An image sensing device includes a pixel array having a plurality of pixels each including first and second photoelectric converters that share a microlens, a plurality of column signal lines, and a readout circuit including a plurality of column circuits each configured to receive a signal of a corresponding column signal line. Each pixel includes first and second driving elements respectively configured to output signals corresponding to charges respectively generated by the first and second photoelectric converters to a corresponding column signal line. In a state in which signals are output from both the first and second driving elements included in a selected pixel to a column signal line corresponding to each of the plurality of column circuits, the readout circuit reads out a signal of the column signal line corresponding to the column circuit.