At design time, cross-jurisdiction workload controls may be presented by a process platform server to a user (e.g., a workload creator or process builder) who is using the process platform to create or update an application having a workload functionality with zero, one, or more applicable regulation controls. If no regulation control is selected, or if there is no exception provided, the process platform server may operate to block the user from proceeding to complete the workload creation process. The application with the workload thus created/updated is delivered to end user(s). Responsive to a user request to open the application on a client device, a server (the process platform server or an application gateway server) may operate to automatically determine whether a target location associated with the user request is permitted in accordance with a cross-jurisdiction workload control associated the workload defined in the application.