A strobe signal generation circuit includes a trigger circuit configured to generate a pull-up signal and a pull-down signal according to a clock signal; a first main driver configured to generate a differential data strobe signal in response to receiving the pull-up signal and the pull-down signal; and a second main driver configured to generate an other differential data strobe signal in response to receiving the pull-up signal and the pull-down signal from among the at least one pull-down signal through opposite terminals than the first main driver received the pull-up signal and the pull-down signal.