A hardware encryption housing and a payment device using the hardware encryption housing includes a top shell, a bottom shell, a circuit board and a trigger switch configured to transmit a trigger signal when the top shell is separated from the bottom shell. A security chip, mounted on the circuit board, has a storage module configured to store key information and a detection module configured to clear the key information and lock the security chip after the trigger signal is detected. The trigger signal is transmitted when the top shell is separated from the bottom shell, and the detection module is provided in the security chip to detect whether the trigger switch transmits a trigger signal. When detected, the key information in the storage module is cleared and the security chip is locked.