A temperature control system includes first and second temperature control devices. In the first temperature control device, a refrigeration circuit of a refrigeration device, which is positioned downstream of an expansion valve and upstream of an evaporator, and a brine circulation path of a brine circulation device, which is positioned on a heating unit, constitutes a refrigeration capacity adjustment mechanism, and cooling is performed by the evaporator of the refrigeration circuit. In the second temperature control device, a refrigeration device includes an injection circuit that bypasses a condensed refrigerant upstream of a compressor, and a hot gas circuit that bypasses a compressed high-temperature refrigerant upstream of a compressor. A part of the brine circulation path of the brine circulation device and an evaporator of the refrigeration device constitute a heating capacity adjustment heat exchanger, and heating or cooling is performed by a load unit of the brine circulation path.