Invention Grant
- Patent Title: Use of oil and water emulsions for increasing B cell responses with modified Vaccinia Ankara virus
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Application No.: US15125388Application Date: 2015-03-12
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Publication No.: US10653766B2Publication Date: 2020-05-19
- Inventor: Cédric Cheminay , Robin Steigerwald , Ariane Volkmann
- Applicant: Bavarian Nordic A/S
- Applicant Address: DK Kvistgaard
- Assignee: Bavarian Nordic A/S
- Current Assignee: Bavarian Nordic A/S
- Current Assignee Address: DK Kvistgaard
- International Application: PCT/EP2015/055239 WO 20150312
- International Announcement: WO2015/136056 WO 20150917
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/21 ; A61K39/02 ; A61K38/00 ; A61K39/395 ; A61K39/12 ; A61K39/285 ; A61K39/155
Abstract:
The invention relates to compositions, uses, and methods for inducing an immune response against a vaccinia virus. The addition of an oil and water emulsion to MVA can vastly increase the B cell response and particularly neutralizing antibodies against vaccinia virus and encoded recombinant antigens. Thus, the addition of an oil and water emulsion to MVA can increase the protective immune response. The invention encompasses administering a dose of an MVA in an oil and water emulsion to an animal, especially a human.
Public/Granted literature
- US20170128561A1 USE OF OIL AND WATER EMULSIONS FOR INCREASING B CELL RESPONSES WITH MODIFIED VACCINIA ANKARA VIRUS Public/Granted day:2017-05-11
Information query
