In various implementations, a method includes obtaining a target image having a first resolution and comprising a plurality of target pixels having a plurality of corresponding target pixel values, obtaining a guide image having a second resolution and comprising a plurality of guide pixels having a plurality of corresponding guide pixel values, and generating an enhanced target image based on the target image and the guide image, the enhanced target image having the second resolution and comprising a plurality of enhanced target pixels having a plurality of corresponding enhanced target pixel values. In various implementations, determining, for a particular upscaled target pixel, a similarity metric indicative of the similarity of a neighborhood of pixels around the particular upscaled target pixel to a neighborhood of pixels around a corresponding guide pixel, and determining, for the particular upscaled target pixel, an enhanced target pixel value based on the similarity metric.