More than one set of sounding signal configuration parameters are determined for the same mobile terminal. The mobile terminal uses the sets of configuration parameters to generate different sounding reference signals which can be used for different purposes such as estimating timing and channel quality. In one embodiment, a method of configuring uplink sounding transmissions by mobile terminals in a wireless communication network is characterized by determining different sets of configuration parameters for sounding signal transmissions for a given mobile terminal. The different sets of configuration parameters are transmitted to the mobile terminal, allowing the mobile terminal to generate different sounding signals for different uses by the wireless communication network.