A two-phase fluid heat transfer structure includes: at least one evaporator having an evaporation chamber, which containing a first working medium; at least one evaporator tube body having a first end and a second end, which communicating with the at least one evaporator to form a loop of the first working medium, the at least one evaporator tube body further having a condensation section between the first and second ends; at least one heat sink; at least one heat sink tube body having a heat absorption section, which containing a second working medium, the at least one heat sink tube body being connected to the at least one heat sink; and at least one heat exchanger having a first face and a second face for the condensation section of the evaporator tube body and the heat absorption section of the heat sink tube body to attach to.