A multi-stage transmission for a vehicle is provided. The multi-stage transmission includes an input shaft and an output shaft. A first planetary gear set, a second planetary gear set, a third planetary gear set, and a fourth planetary gear set each have three rotary elements and transmit torque between the input shaft and the output shaft. At least six shifting elements are connected with the rotary elements of the planetary gear sets. Accordingly, fuel efficiency is improved by implementing multi-stages in an automatic transmission and vehicle driving comfort is improved by using operating points in a low RPM range of an engine.