Invention Grant
- Patent Title: Human plasma kallikrein inhibitors
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Application No.: US15764071Application Date: 2016-09-30
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Publication No.: US10562850B2Publication Date: 2020-02-18
- Inventor: Pravin L. Kotian , Yarlagadda S. Babu , V. Satish Kumar , Weihe Zhang , Lakshminarayana Vogeti
- Applicant: BioCryst Pharmaceuticals, Inc.
- Applicant Address: US NC Durham
- Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee: BioCryst Pharmaceuticals, Inc.
- Current Assignee Address: US NC Durham
- Agency: Foley Hoag LLP
- Agent Dana M. Gordon
- International Application: PCT/US2016/054619 WO 20160930
- International Announcement: WO2017/059178 WO 20170406
- Main IPC: C07D401/14
- IPC: C07D401/14 ; C07D207/12 ; A61K31/444 ; A61K31/40 ; C07D207/16 ; C07D401/12 ; C07D409/14 ; C07D207/24 ; A61P17/00
Abstract:
Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also provided are pharmaceutical compositions comprising at least one compound of the invention, and methods involving use of the compounds and compositions of the invention in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity.
Public/Granted literature
- US20180362458A1 HUMAN PLASMA KALLIKREIN INHIBITORS Public/Granted day:2018-12-20
Information query
