Invention Grant
- Patent Title: Live attenuated virus vaccines for La Crosse virus and other bunyaviridae
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Application No.: US16240222Application Date: 2019-01-04
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Publication No.: US10561724B2Publication Date: 2020-02-18
- Inventor: Stephen S. Whitehead , Richard S. Bennett , Brian R. Murphy
- Applicant: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
- Applicant Address: US MD Bethsda
- Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Bethsda
- Agency: Klarquist Sparkman, LLP
- Main IPC: A61K39/12
- IPC: A61K39/12 ; C12Q1/70 ; C07K14/005 ; C12N7/00 ; A61K39/00
Abstract:
The invention relates to vaccine compositions including CEV serogroup immunogens, attenuated and inactivated viruses of the CEV serogroup and chimeric Bunyaviridae. Also disclosed are methods of treating or preventing CEV serogroup infection in a mammalian host, methods of producing a subunit vaccine composition or an immunogenic composition, isolated polynucleotides comprising a nucleotide sequence encoding a CEV serogroup immunogen, methods for detecting La Crosse virus (LACV) infection in a biological sample and infectious chimeric Bunyaviridae.
Public/Granted literature
- US20190117762A1 LIVE ATTENUATED VIRUS VACCINES FOR LA CROSSE VIRUS AND OTHER BUNYAVIRIDAE Public/Granted day:2019-04-25
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