Invention Grant
- Patent Title: Double-stranded nucleic acid molecule, DNA, vector, cancer cell growth inhibitor, cancer cell migration inhibitor, and drug
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Application No.: US15318576Application Date: 2015-06-12
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Publication No.: US10561679B2Publication Date: 2020-02-18
- Inventor: Satoshi Inoue , Kazuhiro Ikeda , Kuniko Inoue
- Applicant: SAITAMA MEDICAL UNIVERSITY
- Applicant Address: JP Iruma-Gun, Saitama
- Assignee: SAITAMA MEDICAL UNIVERSITY
- Current Assignee: SAITAMA MEDICAL UNIVERSITY
- Current Assignee Address: JP Iruma-Gun, Saitama
- Agency: Buchanan, Ingersoll & Rooney PC
- Priority: JP2014-122067 20140613
- International Application: PCT/JP2015/067054 WO 20150612
- International Announcement: WO2015/190606 WO 20151217
- Main IPC: C12N15/113
- IPC: C12N15/113 ; A61K31/713 ; A61P35/04 ; A61K31/7105 ; A61K31/711

Abstract:
A double-stranded nucleic acid molecule for suppressing expression of non-coding RNA, the double-stranded nucleic acid molecule including: (a) a sense strand containing a nucleotide sequence corresponding to a target sequence set forth in any one of SEQ ID NOs: 5 to 11 and 26 to 31; and (b) an antisense strand containing a nucleotide sequence which is complementary to the sense strand in the (a) to form a double strand with the sense strand, wherein the non-coding RNA contains a base sequence set forth in any one of SEQ ID NOs: 1 to 4, a part of the base sequence, or both of the base sequence and the part.
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