The present invention is notably directed to a flow cell device. The device comprises: an exchange membrane, extending essentially in a plane; an adhesive, at a periphery of the membrane; and two half-cells, each on a respective side of said plane, the half-cells sandwiching the membrane. The membrane spans a smaller area than each of the areas of the half-cells, whereby a peripheral space is defined at the periphery of the membrane between two opposing faces of the half-cells. This space is at least partly filled with an adhesive, so as to secure the two half-cells to each other with the membrane encapsulated therein. The present invention is further directed to a method of fabrication of such a flow cell device.