An artificial intelligence advisory system for vibrant constitutional guidance includes a diagnostic engine operating on at least a server and configured to receive at least a biological extraction from a user and generate a diagnostic output, based on the at least a biological extraction, including at least a prognostic label and at least an ameliorative process label. The system includes a plan generation module configured to generate, based on the diagnostic output, a comprehensive instruction set, associated with the user, including at least a current prognostic descriptor and at least an ameliorative process descriptor. The system includes client-interface module designed and configured to transmit the comprehensive instruction set to at least a user client device. The system includes at least an advisory module configured to generate at least an advisory output as a function of the comprehensive instruction set and transmit the advisory output to at least an advisor client device.