A computing system may evaluate the operation of a manufacturing network using at least two of (a) macro-level threshold criteria indicating anomalous operation of the manufacturing network as a whole, (b) micro-level threshold criteria indicating anomalous operation of any of a plurality of micro-networks in the manufacturing network, (c) path-level threshold criteria indicating anomalous operation of any of a plurality of node paths in the manufacturing network, or (d) node-level threshold criteria indicating anomalous operation of any of a plurality of individual nodes in the manufacturing network. Based on the evaluating, computing system may identify at least one anomaly in the manufacturing network and then trigger at least one action that is directed to resolving the at least one anomaly.