Invention Grant
- Patent Title: Blockade of CD7 expression and chimeric antigen receptors for immunotherapy of T-cell malignancies
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Application No.: US15821170Application Date: 2017-11-22
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Publication No.: US10550183B2Publication Date: 2020-02-04
- Inventor: Yi Tian Png , Natasha Vinanica , Takahiro Kamiya , Dario Campana
- Applicant: National University of Singapore
- Applicant Address: SG Singapore
- Assignee: National University of Singapore
- Current Assignee: National University of Singapore
- Current Assignee Address: SG Singapore
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61P35/02 ; A61K35/17 ; C07K14/725 ; C07K14/705 ; C07K16/30 ; A61K38/00
Abstract:
The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
Public/Granted literature
- US20180148506A1 BLOCKADE OF CD7 EXPRESSION AND CHIMERIC ANTIGEN RECEPTORS FOR IMMUNOTHERAPY OF T-CELL MALIGNANCIES Public/Granted day:2018-05-31
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