Invention Grant
- Patent Title: Compositions and methods for treating cancer with anti-mesothelin immunotherapy
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Application No.: US16252158Application Date: 2019-01-18
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Publication No.: US10550179B2Publication Date: 2020-02-04
- Inventor: Rimas J. Orentas , Dina Schneider , Boro Dropulic , Dimiter S. Dimitrov , Zhongyu Zhu
- Applicant: Lentigen Technology Inc. , The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Applicant Address: US MD Gaithersburg US MD Bethesda
- Assignee: Lentigen Technology Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Current Assignee: Lentigen Technology Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- Current Assignee Address: US MD Gaithersburg US MD Bethesda
- Agency: Fish & Richardson P.C.
- Agent Serge Sira, Esq.
- Main IPC: C12N15/62
- IPC: C12N15/62 ; C12N15/63 ; C12N15/09 ; C12N15/10 ; C12N5/0783 ; C07K16/28 ; C07K16/30 ; C07K14/705 ; C07K14/725 ; A61K35/17 ; A61K39/395 ; C07K16/18 ; A61P35/02 ; A61P35/00
Abstract:
Chimeric antigen receptors containing mesothelin antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.
Public/Granted literature
- US20190218280A1 Compositions and Methods for Treating Cancer with Anti-Mesothelin Immunotherapy Public/Granted day:2019-07-18
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