Invention Grant
- Patent Title: Liposome formulations
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Application No.: US14422587Application Date: 2013-08-15
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Publication No.: US10548841B2Publication Date: 2020-02-04
- Inventor: Arturo Santos , Phillip Frost
- Applicant: OPKO Pharmaceuticals, LLC
- Applicant Address: US FL Miami
- Assignee: OPKO Pharmaceuticals, LLC
- Current Assignee: OPKO Pharmaceuticals, LLC
- Current Assignee Address: US FL Miami
- Agency: OPKO Pharmaceuticals, LLC
- Agent Monte R. Browder
- International Application: PCT/US2013/055084 WO 20130815
- International Announcement: WO2014/031429 WO 20140227
- Main IPC: A61K9/127
- IPC: A61K9/127 ; C07K16/22 ; A61K9/00 ; A61K31/58 ; A61K39/395 ; A61K45/06 ; A61K39/00

Abstract:
The present invention relates to pharmaceutical formulations comprising an anti angiogenic compound such as a monoclonal antibody or fragment thereof selected from, for example, ranibizumab, which is a vascular endothelial growth factor binder which inhibits the action of VEGF, and a delivery agent selected from a pharmaceutically acceptable liposome. The formulations are useful in the treatment of a variety of angiogenic disorders and diseases in animals and people, and, preferably, in ophthalmic disorders selected from age-related macular degeneration, diabetic macular edema and corneal neovascularization.
Public/Granted literature
- US20150224055A1 LIPOSOME FORMULATIONS Public/Granted day:2015-08-13
Information query