A soft-start control circuit includes first to third inverters, first to third comparators, first to fourth resistors, first to fourth D-type flip-flops and a NOR gate. The first comparator outputs a first trigger signal. The second comparator outputs a second trigger signal. The third comparator outputs a third trigger signal. The first D-type flip-flop outputs a first error amplification ready signal. The second D-type flip-flop outputs a second error amplification ready signal. The third D-type flip-flop outputs a high-level output voltage ready signal. The fourth D-type flip-flop outputs a low-level output voltage ready signal. The NOR gate receives an inverted signal of a high-level output voltage enable signal and the third trigger signal and outputs a high-level output voltage control signal to prevent an inrush current of the DC-DC conversion system during a startup process.